Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

As tough as medieval chainmail armor and as soft as a contact lens. This material is not taken from science fiction, it is a ...

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

James D. Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped light the long fuse on a revolution in medicine, crimefighting, genealogy and ethics, has died, according to ...

For James Watson, DNA was everything — not just his life's work, but the secret of life itself. Over his long and storied career, Watson arguably did more than any other scientist to transform a ...