The classic pRb pathway comprises pRb, the E2F family of transcription factors, cyclins (primarily D type), cyclin-dependent kinases (CDKs; primarily 4 and 6), and two families of CDK inhibitors ...
Osteoblasts are the cells required for bone synthesis and mineralization, both during the initial formation of bone and during bone remodelling. These cells are present on the bone surface in the form ...
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