Injury to the podocyte results in proteinuria and often leads to progressive kidney disease. As podocytes have limited ability to repair and/or regenerate, the extent of podocyte injury is a major ...

Two types of parietal podocyte were previously described in the Bowman capsule: one characterized by coexpression of podocyte and parietal epithelial cell markers, the other characterized by ...

While diabetes has long been known to harm the kidneys, this study confirms that high blood pressure can also cause direct ...

In patients with chronic kidney disease, the loss of podocytes—part of the kidney's glomerular filtration barrier—causes irreversible disease progression. So far, physicians and researchers have found ...

Senior Postdoctoral Research Fellow, GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology, Children's Hospital Los Angeles The glomerular filtration barrier, generated ...

A fasting-mimicking diet may promote renoprotection by reducing proteinuria and improving endothelial function. Cycles of controlled fasting may promote regeneration of podocytes in patients with ...

Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.

A unique tool for the study of human glomerular disease. It is known and used worldwide by leading research groups and many of the world’s largest pharmaceutical companies. This conditionally ...

University of Florence–led investigators report that estrogen-regulated renal progenitor cells shape pregnancy adaptation in mice with failure of estrogen receptor alpha signaling precipitating ...

A study published in Advanced Healthcare Materials describes the bioengineering of three-dimensional (3D) kidney glomerular microtissues that replicate the glomerular filtration barrier (GFB) ...