A research team has unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve. Rice University's Peter Wolynes and his research team have unveiled a ...

Life’s most indispensable molecules are not the serene, unchanging fixtures they might appear to be. Even the proteins that ...

Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique ...

A new platform combines rational protein design with continuous evolution to discover functional molecules more efficiently. In medicine and biotechnology, the ability to evolve proteins with new or ...

Synthesizing new proteins – the building blocks of biological life – is a scientific field of immense potential, and a newly developed AI model promises to create instructions for new proteins way ...

Scientists have developed a novel approach to modifying enzymes to improve functionality. They designed a new algorithm to make multiple changes to an enzyme sequence at once as compared to the ...

Up-to-date computational pipeline characterizes G-protein-coupled receptor (GPCR) repertoires in the closest relatives of metazoans, providing a framework to investigate the evolutionary origins and ...

In a remarkable leap forward for synthetic biology, the AI model ESM3, developed by Evolutionary Scale, has achieved a significant milestone. By simulating half a billion years of evolutionary ...

The stability of ribonucleoprotein complexes of SARS-CoV-2 nucleocapsid proteins differs among variants of concern and the viral evolution of nucleocapsid protein can be understood in the framework of ...