Praxis Precision Medicines' ulixacaltamide (PRAX-944) is a potent and selective small molecule T-type Ca2+ channel blocker being developed for the potential treatment of essential tremor. ET is a ...

Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, according to a ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

Certain everyday foods can interfere with blood pressure medications, increasing side effects or reducing their effectiveness ...

Examining data on more than 400,000 participants in the U.K. Biobank revealed that use of CCBs was associated with a 39% greater odds of glaucoma after adjusting for various factors, including the use ...

Little additional work has been performed beyond that of Lee et al. [1,3,10] to further investigate the proposed dual action of ibutilide. Our laboratory has sought to examine the effects of sodium ...

Use of calcium channel blockers (CCBs), particularly cardioselective agents, had a modest but statistically significant association with glaucoma, a large meta-analysis showed. Overall, patients with ...