Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesineConvergence of impaired ...

This valuable study presents a plastic recurrent spiking network model that spontaneously generates repeating neuronal sequences under unstructured inputs. The authors provide solid evidence that, ...

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song or directions to a friend's house become encoded in our brains? The broad answer is that our brains undergo ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...

Researchers have settled a 60-year-old debate in neuroscience, proving that the visual cortex constructs complex images from ...

There's a lot to love about coffee. From its delicious taste to its utterly intoxicating aroma, and the social ritual of ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

For decades, the scientific theory of depression focused on chemicals — serotonin, norepinephrine and dopamine. Nearly every ...