RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Torino is a computational workflow that uses biobank-scale RNA-seq data to decode transcript structures and expression levels from read coverage alone.

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

Clonal hematopoiesis of indeterminate potential (CHIP) is a known risk factor for coronary artery disease, though its precise role in disease progression continues to emerge. This study leverages ...

ETH Zurich scientists have created “MetaGraph,” a revolutionary DNA search engine that functions like Google for genetic data. By compressing global genomic datasets by a factor of 300, it allows ...

Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in ...

A new computational tool developed by researchers has uncovered genetic evidence directly linking Alzheimer’s disease to the ...

Researchers have uncovered genetic elements that drive the rapid development of marsupials' facial features. Subscribe to our ...

The company says the system can benefit pharmaceutical and biotech firms seeking rapid feedback on drug candidates or genome editing.

Scientists found a virus-like living entity in human bodies named "obelisks" - small loops of RNA, each a thousand genetic ...