Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, ...

About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane ...

The NEURL E3 ubiquitin ligases selectively activate the Notch ligands DLL1 and JAG1, but not DLL4 and JAG2. This differential ...

Tiny viruses that only infect and kill bacteria can help treat deadly antibiotic-resistant bloodstream infections with ...

Study sets stage for development of synthetic biosensors with custom-built sensing and responses for basic and translational cell engineering applications.

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), ...

Deciphering how the GR forms oligomers—through the binding of several subunits—opens a crucial avenue for developing more ...

A new study has revealed the mechanism of multimerization — the association of different molecules to form complex structures ...

So far, immune cells that have been engineered to kill cancers, known as CAR T-cells, haven’t worked well against solid ...

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - ...

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, ...

Peroxisomes are essential cell organelles that play a vital role in lipid metabolism and cellular detoxification. To perform ...