UPS Flight 2976 crashed around 5:15 p.m. local time on Tuesday, Nov. 4, after departing from Louisville Muhammad Ali International Airport in Kentucky. The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu. The FAA and NTSB will investigate. The NTSB will lead the investigation and will provide all updates.

Video of the deadly crash showed flames on one of the plane's wings, and a huge fireball erupting as the aircraft hit the ground.

Video showed flames on the plane’s left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball.

At least seven people have now been confirmed dead with the death toll expected to rise following the 'catastrophic' UPS plane crash in Louisville, Kentucky on Nov. 4.

After the UPS plane crash there were still at least 9 people dead as of Wednesday, according to Kentucky Gov. Andy Beshear.

Jefferson County Public Schools says school will be canceled on WednesdaY due to the shelter-in-place order following the UPS plane crash at Muhammad Ali International Airport in Louisville.

Video shows massive fireball and smoke after UPS Flight 2976 crashed into Kentucky Petroleum Recycling building during takeoff at Louisville airport.

A UPS MD-11 plane crashed near the Louisville Muhammad Ali International Airport in Louisville, Ky., on Tuesday, Nov. 4. The crash caused a fire, prompting local agencies to issue a shelter-in-place alert.