The 49ers (3-0) won their home opener 16-15 on Eddy Pineiro’s walk-off field goal against the Arizona Cardinals.

Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from September 21, 2025 on ESPN.

San Fransisco 49ers OC Klint Kubiak addressed the media on Thursday and discussed the injury status of QB Brock Purdy, offering a vague update.

“Head coach Kyle Shanahan confirmed Monday that defensive lineman Nick Bosa suffered a torn ACL in his right knee during Sunday's win over the Arizona Cardinals. Bosa will undergo season-ending ...

The San Francisco 49ers and Arizona Cardinals are set to kick off on Sunday, and they'll be without a few players, who have been deemed inactive.

In a battle featuring two teams with two injury-depleted rosters, the San Francisco 49ers proved to be the one with much more ...

At 2-5, the Arizona Cardinals face a tall and difficult task to turn things around, and, in predicting how it will end, it's ...

The NFC West didn't see their Week 7 action end until late Monday night, as the Seattle Seahawks played the final game of the ...

The San Francisco 49ers have released their final injury report for their matchup with the New York Giants. Here is the bad, but expected news. Ricky Pearsall ( ...

Kyler Murray has missed two straight games for the reeling Arizona Cardinals who have lost five straight after starting the season 2-0. Now, with their season in the balance, the Cards await the ...

The San Francisco 49ers have gotten out to a fairly improbable 2-0 start this season. The same can be said for their Week 3 opponent, the Arizona Cardinals. The players listed below will be ones to ...

The San Francisco 49ers finished their Week 7 contest with a 20-10 win over the Atlanta Falcons on "Sunday Night Football" at ...