Life just got more difficult for those fighting antibiotic-resistant superbugs. Researchers at McGill University have ...

Preclinical study showed PDIA1 and PDIA5 protect cells from oxidative stress, maintain mitochondrial function, and are ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Researchers studied a trypsin inhibitor from tamarind seeds (TTI) in Brazil to find new ways to control blood sugar TTI directly inhibited α-amylase, an enzyme that breaks down carbohydrates, by over ...

No safety concerns or dose limiting toxicities observed, pharmacodynamic analysis demonstrated evidence of dose dependent target engagement together with a biologic effect SAN DIEGO--(BUSINESS ...

Having already stripped back their development plans for the estrogen receptor (ER) degrader vepdegestrant on the back of mixed data, Pfizer and Arvinas have now decided to wash their hands of the ...

The authors developed a methodology to graph antigenic surface loops on influenza virus neuraminidases. The hybrid proteins retained the structure of the neuraminidase scaffold and the antigenicity of ...

(Alliance News) - Aptamer Group PLC shares jumped on Friday as the firm said it has made progress across its enzyme modulation projects, including advancing its second inhibitor to the final ...

Seven months after pressing pause on its plans for its PKMYT1 inhibitor, Repare Therapeutics has found a partner to take the cancer drug forward. Back in January, Repare abandoned phase 3 plans to ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

A recent study from Stanford Medicine that "totally surprised" researchers highlighted what could be a promising approach to slowing Parkinson’s disease progression. The research, published in the ...