Accuracy test for protein language models shines light into AI 'black box'

AI language models, used to generate human-like text to power chatbots and create content, are also revolutionizing biology ...
Purdue University

Small segments of RNA halt cancer in multiple ways

Like tiny superheroes, small, naturally occurring segments of RNA can block multiple molecular paths that cancer cells use to ...
Princeton University

David Botstein, a leader of the Human Genome Project, dies at 83

Botstein, Princeton’s Anthony B. Evnin ‘62 Professor of Genomics, Emeritus, and an emeritus professor of molecular biology ...
IEEE

Optimizing Machine Learning Models for Renal Cancer Diagnosis from Gene Expression Microarrays

Abstract: The accurate diagnosis and personalized treatment of renal cancer are significant challenges due to its complexity and heterogeneity. Machine learning (ML) techniques have opened new avenues ...
IEEE

Selection of Robust Feature Selection Methods Used for Gene Expression Analysis of Microarray Data

Abstract: Experimental genomics involves a series of techniques and methodologies aimed at analysing the organization and behaviour of genes and genomes. Microarrays have a large number of nucleic ...
BioSpace

Taysha Gene Therapies Presents New Supplemental Data Analysis from Part A of the REVEAL Phase 1/2 Trials for TSHA-102 in Rett Syndrome at the 54th CNS Annual Meeting

Previously disclosed 100% response rate across all 10 patients in Part A for pivotal trial primary endpoint of gain/regain of ≥ one natural history defined developmental milestone assessed via ...
EurekAlert!

Microarray analysis of differential expression of long non-coding RNAs in peripheral blood mononuclear cells in luminal a breast cancer

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers. This study aimed to ...
ascopubs.org

Amivantamab treatment and intra-tumoral gene expression and immune cell changes in refractory metastatic colorectal cancer (mCRC): Whole transcriptome RNA-sequencing analysis ...

Outcomes of young-onset colorectal cancer vs late-onset colorectal cancer patients on phase 1 matched and non-matched therapies. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.
ascopubs.org

Co-expression network-based analysis of gene programs contributing to immune checkpoint inhibitor (ICI) resistance in renal cell carcinoma (RCC).

Phase 1 results of Oncobax-AK in combination with ipilimumab/nivolumab in advanced clear cell renal cell carcinoma (ccRCC; NCT05865730). This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...