Pinetree Therapeutics Raises $47 Million in Oversubscribed Series B to Advance Next-Generation Protein Degraders in Oncology

Pinetree Therapeutics, a preclinical-stage biotechnology company pioneering targeted protein degraders for drug-resistant cancers, announced the successful closing of an oversubscribed $47 million ...
C&EN

Biosynthesis, Chemical Synthesis, and Pharmacological Evaluation of Lyngbyapeptin A as a GPCR Antagonist of Motilin, Cannabinoid, and Amylin Receptors

Department of Medicinal Chemistry, University of Florida, Gainesville, Florida 32610, United States Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, ...
IEEE

GIVL-SLAM: A Robust and High-Precision SLAM System by Tightly Coupled GNSS RTK, Inertial, Vision, and LiDAR

Abstract: In this article, we present GIVL-SLAM, a factor graph optimization-based framework that tightly fuses double-differenced pseudorange and carrier phase observations of the GNSS with inertial, ...
News Medical

GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans

The growing use of GLP-1 receptor agonists may affect the interpretation of oncological FDG PET-CT scans, new research presented today at the 38th Annual Congress of the European Association of ...
eLife

Non-equilibrium strategies enabling ligand specificity by signaling receptors

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...