Kinase target engagement assays and kinase-NanoLuc® luciferase fusion vectors to measure kinase-compound binding and residence time in live cells.

Apr 3, 2020 · The inhibition profile for each kinase provides a fingerprint that allows identification of unknown kinases acting on target phosphosites in cell extracts.

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Description The NanoBRET® Target Engagement (TE) Assay(a–f) (Figure 1) measures compound binding at select target proteins within intact cells (1). The NanoBRET® TE Assay has been applied …

Kinase Screening and Profiling Services With more than two decades of experience in kinase drug discovery, Eurofins Discovery has developed the industry’s largest collection of biochemical and cell …