May 27, 2025 · You may have heard that if you have an MTHFR variant, you should avoid folic acid and should take other types of folate, such as 5-MTHF. However, this is not true.

Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. [5] Methylenetetrahydrofolate reductase catalyzes the conversion of …

Feb 25, 2025 · The abbreviation MTHFR refers to a relatively common genetic mutation. It stands for methylenetetrahydrofolate reductase, and having this mutation may lead to high levels of …

Aug 21, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may contribute to …

MTHFR gene mutation affects folate metabolism, linked to higher risk of cardiovascular issues, blood clots, and certain birth defects. It influences methylation and homocysteine levels.

MTHFR is a gene that makes an enzyme called MethyleneTetraHydroFolate Reductase. This enzyme works with a B-vitamin called folate. Together, MTHFR and folate help to reduce the level of …

Nov 10, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme produced by the MTHFR gene. MTHFR interacts with folate (vitamin B9) to break down homocysteine so that it can be …

What is methylene tetrahydrofolate reductase (MTHFR)? MTHFR is a gene, not a disease or genetic condition. The MTHFR gene serves many functions. One of its most important functions is providing …

Jun 2, 2025 · Everything on MTHFR gene mutations, impact on health, symptoms, and testing. How MTHFR affects methylation, folate, and homocysteine—plus natural ways to manage it.

Sep 9, 2024 · Read on to learn more about the MTHFR gene mutation symptoms, testing, and treatments. MTHFR gene mutations can cause elevation of blood homocysteine levels, some of …