Acemannan’s biological activity is closely tied to acetylation status, molecular weight, & chain length. When these structural features are intact, acemannan has been shown to interact with pattern-recognition receptors on immune cells, particularly on macrophages, dendritic cells, and natural killer (NK) cells. Rather than overstimulating the immune system, studies describe acemannan as supporting immune communication and coordination, helping immune cells recognize signals, respond appropriate
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Acemannan’s biological activity is closely tied to acetylation status, …
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