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28:31
YouTube
Sarah Bartlett
Oxidation of borneol
A green oxidation of (-)-borneol to borneone (camphor) Objective To oxidize a secondary alcohol to a ketone, a very common synthetic transformation, using relatively environmentally friendly ("green") chemical conditions. In this lab, (-)-borneol will be oxidized to borneone (camphor) using the green oxidizing agent Oxone in the presence of ...
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Mar 25, 2020
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Mechanism for the Oxidation of Borneol to Camphor
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SOLVED:The structure of the bicyclic monoterpene borneol is shown in Figure 25.8. Isoborneol, a stereoisomer of borneol, can be prepared in the laboratory by a two-step sequence. In the first step, borneol is oxidized to camphor by treatment with chromic acid. In the second step, camphor is reduced with sodium borohydride to a mixture of 85 % isoborneol and 15 % borneol. On the basis of these transformations, deduce structural formulas for isoborneol and camphor.
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